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NAG-1/GDF15 Accumulates in the nucleus and modulates transcriptional regulation of the Smad pathway

Protein dynamics, modifications, and trafficking are all processes that can modulate protein activity. Accumulating evidence strongly suggests that many proteins play distinctive roles dependent on cellular location. Nonsteroidal anti-inflammatory drug activated gene-1 (NAG-1) is a TGF-β superfamily...

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Detalles Bibliográficos
Autores principales: Min, K-W, Liggett, JL, Silva, G, Wu, WW, Wang, R, Shen, R-F, Eling, TE, Baek, SJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613816/
https://www.ncbi.nlm.nih.gov/pubmed/25893289
http://dx.doi.org/10.1038/onc.2015.95