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Neuronal and Endothelial Nitric Oxide Synthases in the Paraventricular Nucleus Modulate Sympathetic Overdrive in Insulin-Resistant Rats

A central mechanism participates in sympathetic overdrive during insulin resistance (IR). Nitric oxide synthase (NOS) and nitric oxide (NO) modulate sympathetic nerve activity (SNA) in the paraventricular nucleus (PVN), which influences the autonomic regulation of cardiovascular responses. The aim o...

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Detalles Bibliográficos
Autores principales: Lu, Qing-Bo, Feng, Xue-Mei, Tong, Ning, Sun, Hai-Jian, Ding, Lei, Wang, Yu-Jiao, Wang, Xuan, Zhou, Ye-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613827/
https://www.ncbi.nlm.nih.gov/pubmed/26485682
http://dx.doi.org/10.1371/journal.pone.0140762