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Covalent Modification of Synthetic Hydrogels with Bioactive Proteins via Sortase-Mediated Ligation

[Image: see text] Synthetic extracellular matrices are widely used in regenerative medicine and as tools in building in vitro physiological culture models. Synthetic hydrogels display advantageous physical properties, but are challenging to modify with large peptides or proteins. Here, a facile, mil...

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Detalles Bibliográficos
Autores principales: Cambria, Elena, Renggli, Kasper, Ahrens, Caroline C., Cook, Christi D., Kroll, Carsten, Krueger, Andrew T., Imperiali, Barbara, Griffith, Linda G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613866/
https://www.ncbi.nlm.nih.gov/pubmed/26098148
http://dx.doi.org/10.1021/acs.biomac.5b00549