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Blockade of growth hormone secretagogue receptor 1A signaling by JMV 2959 attenuates the NMDAR antagonist, phencyclidine-induced impairments in prepulse inhibition

RATIONALE: Schizophrenic-spectrum patients commonly display deficits in preattentive information processing as evidenced, for example, by disrupted prepulse inhibition (PPI), a measure of sensorimotor gating. Similar disruptions in PPI can be induced in rodents and primates by the psychotomimetic dr...

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Detalles Bibliográficos
Autores principales: Engel, Jörgen A., Jerlhag, Elisabet, Svensson, Lennart, Smith, Roy G., Egecioglu, Emil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613889/
https://www.ncbi.nlm.nih.gov/pubmed/26319159
http://dx.doi.org/10.1007/s00213-015-4054-3