EphA4 Receptor Forward Signaling Inhibits Glucagon Secretion From α-Cells

The loss of inhibition of glucagon secretion exacerbates hyperglycemia in type 1 and 2 diabetes. However, the molecular mechanisms that regulate glucagon secretion in unaffected and diabetic states remain relatively unexplained. We present evidence supporting a new model of juxtacrine-mediated regul...

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Detalles Bibliográficos
Autores principales: Hutchens, Troy, Piston, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613968/
https://www.ncbi.nlm.nih.gov/pubmed/26251403
http://dx.doi.org/10.2337/db15-0488

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613968/
https://www.ncbi.nlm.nih.gov/pubmed/26251403
http://dx.doi.org/10.2337/db15-0488

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