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EphA4 Receptor Forward Signaling Inhibits Glucagon Secretion From α-Cells
The loss of inhibition of glucagon secretion exacerbates hyperglycemia in type 1 and 2 diabetes. However, the molecular mechanisms that regulate glucagon secretion in unaffected and diabetic states remain relatively unexplained. We present evidence supporting a new model of juxtacrine-mediated regul...
Autores principales: | Hutchens, Troy, Piston, David W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613968/ https://www.ncbi.nlm.nih.gov/pubmed/26251403 http://dx.doi.org/10.2337/db15-0488 |
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