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Phenotypic Characterization of MIP-CreERT(1Lphi) Mice With Transgene-Driven Islet Expression of Human Growth Hormone

There is growing concern over confounding artifacts associated with β-cell–specific Cre-recombinase transgenic models, raising questions about their general usefulness in research. The inducible β-cell–specific transgenic (MIP-CreERT(1Lphi)) mouse was designed to circumvent many of these issues, and...

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Detalles Bibliográficos
Autores principales: Oropeza, Daniel, Jouvet, Nathalie, Budry, Lionel, Campbell, Jonathan E., Bouyakdan, Khalil, Lacombe, Julie, Perron, Gabrielle, Bergeron, Valerie, Neuman, Joshua C., Brar, Harpreet K., Fenske, Rachel J., Meunier, Clemence, Sczelecki, Sarah, Kimple, Michelle E., Drucker, Daniel J., Screaton, Robert A., Poitout, Vincent, Ferron, Mathieu, Alquier, Thierry, Estall, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4613972/
https://www.ncbi.nlm.nih.gov/pubmed/26153246
http://dx.doi.org/10.2337/db15-0272