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Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR

Placental amino acid transport is decreased in intrauterine growth restriction (IUGR); however, the underlying mechanisms remain largely unknown. We have shown that mechanistic target of rapamycin (mTOR) signalling regulates system A amino acid transport by modulating the ubiquitination and plasma m...

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Detalles Bibliográficos
Autores principales: Chen, Yi-Yung, Rosario, Fredrick J., Shehab, Majida Abu, Powell, Theresa L., Gupta, Madhulika B., Jansson, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614027/
https://www.ncbi.nlm.nih.gov/pubmed/26374858
http://dx.doi.org/10.1042/CS20150511