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Zwint-1 is required for spindle assembly checkpoint function and kinetochore-microtubule attachment during oocyte meiosis

The key step for faithful chromosome segregation during meiosis is kinetochore assembly. Defects in this process result in aneuploidy, leading to miscarriages, infertility and various birth defects. However, the roles of kinetochores in homologous chromosome segregation during meiosis are ill-define...

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Detalles Bibliográficos
Autores principales: Woo Seo, Dong, Yeop You, Seung, Chung, Woo-Jae, Cho, Dong-Hyung, Kim, Jae-Sung, Su Oh, Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614028/
https://www.ncbi.nlm.nih.gov/pubmed/26486467
http://dx.doi.org/10.1038/srep15431