Selective inhibition of dopamine‐beta‐hydroxylase enhances dopamine release from noradrenergic terminals in the medial prefrontal cortex

INTRODUCTION: Disulfiram has been claimed to be useful in cocaine addiction therapy, its efficacy being attributed to dopamine‐beta‐hydroxylase (DBH) inhibition. Our previous results indicate that disulfiram and the selective DBH inhibitor nepicastat increase extracellular dopamine (DA) in the rat m...

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Detalles Bibliográficos
Autores principales: Devoto, Paola, Flore, Giovanna, Saba, Pierluigi, Frau, Roberto, Gessa, Gian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614051/
https://www.ncbi.nlm.nih.gov/pubmed/26516613
http://dx.doi.org/10.1002/brb3.393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614051/
https://www.ncbi.nlm.nih.gov/pubmed/26516613
http://dx.doi.org/10.1002/brb3.393

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