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Persistent astrocyte activation in the fragile X mouse cerebellum

BACKGROUND: Fragile X Syndrome, the most common single gene cause of autism, results from loss of the RNA‐binding protein FMRP. Although FMRP is highly expressed in neurons, it has also recently been identified in glia. It has been postulated that in the absence of FMRP, abnormal function of non‐neu...

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Detalles Bibliográficos
Autores principales: Pacey, Laura K. K., Guan, Sihui, Tharmalingam, Sujeenthar, Thomsen, Christian, Hampson, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614053/
https://www.ncbi.nlm.nih.gov/pubmed/26516618
http://dx.doi.org/10.1002/brb3.400