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A LCMT1-PME-1 methylation equilibrium controls mitotic spindle size

Leucine carboxyl methyltransferase-1 (LCMT1) and protein phosphatase methylesterase-1 (PME-1) are essential enzymes that regulate the methylation of the protein phosphatase 2A catalytic subunit (PP2AC). LCMT1 and PME-1 have been linked to the regulation of cell growth and proliferation, but the unde...

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Detalles Bibliográficos
Autores principales: Xia, Xiaoyu, Gholkar, Ankur, Senese, Silvia, Torres, Jorge Z
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614068/
https://www.ncbi.nlm.nih.gov/pubmed/25839665
http://dx.doi.org/10.1080/15384101.2015.1026487