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Computational evidence that fast translation speed can increase the probability of cotranslational protein folding

Translation speed can affect the cotranslational folding of nascent peptide. Experimental observations have indicated that slowing down translation rates of codons can increase the probability of protein cotranslational folding. Recently, a kinetic modeling indicates that fast translation can also i...

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Detalles Bibliográficos
Autores principales: Wang, Ercheng, Wang, Jun, Chen, Changjun, Xiao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614103/
https://www.ncbi.nlm.nih.gov/pubmed/26486723
http://dx.doi.org/10.1038/srep15316