Abnormal dopaminergic modulation of striato-cortical networks underlies levodopa-induced dyskinesias in humans

Dopaminergic signalling in the striatum contributes to reinforcement of actions and motivational enhancement of motor vigour. Parkinson's disease leads to progressive dopaminergic denervation of the striatum, impairing the function of cortico-basal ganglia networks. While levodopa therapy allev...

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Detalles Bibliográficos
Autores principales: Herz, Damian M., Haagensen, Brian N., Christensen, Mark S., Madsen, Kristoffer H., Rowe, James B., Løkkegaard, Annemette, Siebner, Hartwig R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614130/
https://www.ncbi.nlm.nih.gov/pubmed/25882651
http://dx.doi.org/10.1093/brain/awv096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614130/
https://www.ncbi.nlm.nih.gov/pubmed/25882651
http://dx.doi.org/10.1093/brain/awv096

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