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Direct visualization of alpha-synuclein oligomers reveals previously undetected pathology in Parkinson’s disease brain

Oligomeric forms of alpha-synuclein are emerging as key mediators of pathogenesis in Parkinson’s disease. Our understanding of the exact contribution of alpha-synuclein oligomers to disease is limited by the lack of a technique for their specific detection. We describe a novel method, the alpha-synu...

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Detalles Bibliográficos
Autores principales: Roberts, Rosalind F., Wade-Martins, Richard, Alegre-Abarrategui, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614141/
https://www.ncbi.nlm.nih.gov/pubmed/25732184
http://dx.doi.org/10.1093/brain/awv040