Cargando…

Genomic expression catalogue of a global collection of BCG vaccine strains show evidence for highly diverged metabolic and cell-wall adaptations

Although Bacillus Calmette-Guérin (BCG) vaccines against tuberculosis have been available for more than 90 years, their effectiveness has been hindered by variable protective efficacy and a lack of lasting memory responses. One factor contributing to this variability may be the diversity of the BCG...

Descripción completa

Detalles Bibliográficos
Autores principales: Abdallah, Abdallah M., Hill-Cawthorne, Grant A., Otto, Thomas D., Coll, Francesc, Guerra-Assunção, José Afonso, Gao, Ge, Naeem, Raeece, Ansari, Hifzur, Malas, Tareq B., Adroub, Sabir A., Verboom, Theo, Ummels, Roy, Zhang, Huoming, Panigrahi, Aswini Kumar, McNerney, Ruth, Brosch, Roland, Clark, Taane G., Behr, Marcel A., Bitter, Wilbert, Pain, Arnab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614345/
https://www.ncbi.nlm.nih.gov/pubmed/26487098
http://dx.doi.org/10.1038/srep15443