Rotenone Attenuates Renal Injury in Aldosterone-Infused Rats by Inhibiting Oxidative Stress, Mitochondrial Dysfunction, and Inflammasome Activation

BACKGROUND: Reactive oxygen species (ROS) and inflammation both contribute to the progression of aldosterone-induced renal injury. To better understand the underlying mechanisms, we examined mitochondrial dysfunction and NLRP3 inflammasome activation in aldosterone-infused rats, and explored the rol...

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Detalles Bibliográficos
Autores principales: Ding, Wei, Xu, Chengyan, Wang, Bin, Zhang, Minmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614375/
https://www.ncbi.nlm.nih.gov/pubmed/26474533
http://dx.doi.org/10.12659/MSM.895945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614375/
https://www.ncbi.nlm.nih.gov/pubmed/26474533
http://dx.doi.org/10.12659/MSM.895945

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