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A cancer-associated mutation inactivates a region of the high-mobility group protein HMG20b essential for cytokinesis

Defects in the completion of cell division by cytokinesis have long been proposed to foster carcinogenesis by engendering chromosome instability, but few tumor suppressor mechanisms controlling this process have so far been identified. Here, we identify a carboxyl (C)-terminal region of the high-mob...

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Detalles Bibliográficos
Autores principales: Lee, MiYoung, Venkitaraman, Ashok R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614378/
https://www.ncbi.nlm.nih.gov/pubmed/25486196
http://dx.doi.org/10.4161/15384101.2014.942204