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Ca(2+)/calmodulin regulates Kvβ1.1-mediated inactivation of voltage-gated K(+) channels

A-type K(+) channels open on membrane depolarization and undergo subsequent rapid inactivation such that they are ideally suited for fine-tuning the electrical signaling in neurons and muscle cells. Channel inactivation mostly follows the so-called ball-and-chain mechanism, in which the N-terminal s...

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Detalles Bibliográficos
Autores principales: Swain, Sandip M., Sahoo, Nirakar, Dennhardt, Sophie, Schönherr, Roland, Heinemann, Stefan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614385/
https://www.ncbi.nlm.nih.gov/pubmed/26487174
http://dx.doi.org/10.1038/srep15509