Structure–mechanics relationships of collagen fibrils in the osteogenesis imperfecta mouse model

The collagen molecule, which is the building block of collagen fibrils, is a triple helix of two α1(I) chains and one α2(I) chain. However, in the severe mouse model of osteogenesis imperfecta (OIM), deletion of the COL1A2 gene results in the substitution of the α2(I) chain by one α1(I) chain. As th...

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Detalles Bibliográficos
Autores principales: Andriotis, O. G., Chang, S. W., Vanleene, M., Howarth, P. H., Davies, D. E., Shefelbine, S. J., Buehler, M. J., Thurner, P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614505/
https://www.ncbi.nlm.nih.gov/pubmed/26468064
http://dx.doi.org/10.1098/rsif.2015.0701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614505/
https://www.ncbi.nlm.nih.gov/pubmed/26468064
http://dx.doi.org/10.1098/rsif.2015.0701

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