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Defective mitochondrial fission augments NLRP3 inflammasome activation

Despite the fact that deregulated NLRP3 inflammasome activation contributes to the pathogenesis of chronic inflammatory or metabolic disorders, the underlying mechanism by which NLRP3 inflammasome signaling is initiated or potentiated remains poorly understood. Much attention is being paid to mitoch...

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Detalles Bibliográficos
Autores principales: Park, Sangjun, Won, Ji-Hee, Hwang, Inhwa, Hong, Sujeong, Lee, Heung Kyu, Yu, Je-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614538/
https://www.ncbi.nlm.nih.gov/pubmed/26489382
http://dx.doi.org/10.1038/srep15489