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Mitotic activity of survivin is regulated by acetylation at K129

Survivin is a cancer-associated protein regulated by multiple factors, including acetylation at K129 within its C-terminal α-helical tail. Acetylation of survivin is being pursued as a potential prognostic marker in breast cancer. This modification at K129 may cause nuclear accumulation of survivin...

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Detalles Bibliográficos
Autores principales: Aljaberi, Aysha M, Webster, Jamie RM, Wheatley, Sally P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614551/
https://www.ncbi.nlm.nih.gov/pubmed/25928399
http://dx.doi.org/10.1080/15384101.2015.1033597