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Engineering a pyridoxal 5’-phosphate supply for cadaverine production by using Escherichia coli whole-cell biocatalysis

Although the routes of de novo pyridoxal 5′-phosphate (PLP) biosynthesis have been well described, studies of the engineering of an intracellular PLP supply are limited, and the effects of cellular PLP levels on PLP-dependent enzyme-based whole-cell biocatalyst activity have not been described. To i...

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Detalles Bibliográficos
Autores principales: Ma, Weichao, Cao, Weijia, Zhang, Bowen, Chen, Kequan, Liu, Quanzhen, Li, Yan, Ouyang, Pingkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614675/
https://www.ncbi.nlm.nih.gov/pubmed/26490441
http://dx.doi.org/10.1038/srep15630