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Engineering a pyridoxal 5’-phosphate supply for cadaverine production by using Escherichia coli whole-cell biocatalysis
Although the routes of de novo pyridoxal 5′-phosphate (PLP) biosynthesis have been well described, studies of the engineering of an intracellular PLP supply are limited, and the effects of cellular PLP levels on PLP-dependent enzyme-based whole-cell biocatalyst activity have not been described. To i...
Autores principales: | Ma, Weichao, Cao, Weijia, Zhang, Bowen, Chen, Kequan, Liu, Quanzhen, Li, Yan, Ouyang, Pingkai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614675/ https://www.ncbi.nlm.nih.gov/pubmed/26490441 http://dx.doi.org/10.1038/srep15630 |
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