mTOR kinase-dependent, but raptor-independent regulation of downstream signaling is important for cell cycle exit and myogenic differentiation

Myogenic differentiation in the C2C12 myoblast model system reflects a concerted and controlled activation of transcription and translation following the exit of cells from the cell cycle. Previously we have shown that the mTORC1 signaling inhibitor, RAD001, decreased protein synthesis rates, delaye...

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Detalles Bibliográficos
Autores principales: Pollard, Hilary J, Willett, Mark, Morley, Simon J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614745/
https://www.ncbi.nlm.nih.gov/pubmed/25486193
http://dx.doi.org/10.4161/15384101.2014.941747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614745/
https://www.ncbi.nlm.nih.gov/pubmed/25486193
http://dx.doi.org/10.4161/15384101.2014.941747

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