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PITX1, a specificity determinant in the HIF-1α-mediated transcriptional response to hypoxia
Hypoxia is an important developmental cue for multicellular organisms but it is also a contributing factor for several human pathologies, such as stroke, cardiovascular diseases and cancer. In cells, hypoxia activates a major transcriptional program coordinated by the Hypoxia Inducible Factor (HIF)...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614811/ https://www.ncbi.nlm.nih.gov/pubmed/25558831 http://dx.doi.org/10.4161/15384101.2014.972889 |