Cargando…

PITX1, a specificity determinant in the HIF-1α-mediated transcriptional response to hypoxia

Hypoxia is an important developmental cue for multicellular organisms but it is also a contributing factor for several human pathologies, such as stroke, cardiovascular diseases and cancer. In cells, hypoxia activates a major transcriptional program coordinated by the Hypoxia Inducible Factor (HIF)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mudie, Sharon, Bandarra, Daniel, Batie, Michael, Biddlestone, John, Moniz, Sonia, Ortmann, Brian, Shmakova, Alena, Rocha, Sonia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2015
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614811/ https://www.ncbi.nlm.nih.gov/pubmed/25558831 http://dx.doi.org/10.4161/15384101.2014.972889

Ejemplares similares

HIF-1α restricts NF-κB-dependent gene expression to control innate immunity signals
por: Bandarra, Daniel, et al.
Publicado: (2015)

SINHCAF/FAM60A and SIN3A specifically repress HIF-2α expression
por: Biddlestone, John, et al.
Publicado: (2018)

PBRM1 Cooperates with YTHDF2 to Control HIF-1α Protein Translation
por: Shmakova, Alena, et al.
Publicado: (2021)

Cezanne regulates E2F1-dependent HIF2α expression
por: Moniz, Sonia, et al.
Publicado: (2015)

Hypoxia activates IKK–NF-κB and the immune response in Drosophila melanogaster
por: Bandarra, Daniel, et al.
Publicado: (2014)

Enhanced snoMEN Vectors Facilitate Establishment of GFP–HIF-1α Protein Replacement Human Cell Lines
por: Ono, Motoharu, et al.
Publicado: (2016)

The role of hypoxia in inflammatory disease (Review)
por: BIDDLESTONE, JOHN, et al.
Publicado: (2015)

KDM2 Family Members are Regulated by HIF-1 in Hypoxia
por: Batie, Michael, et al.
Publicado: (2017)

Regulation of chromatin accessibility by hypoxia and HIF
por: Batie, Michael, et al.
Publicado: (2022)

Analysis of Global RNA Synthesis at the Single Cell Level following Hypoxia
por: Biddlestone, John, et al.
Publicado: (2014)

Hypoxia and Inflammation in Cancer, Focus on HIF and NF-κB
por: D’Ignazio, Laura, et al.
Publicado: (2017)

Gene transcription and chromatin regulation in hypoxia
por: Batie, Michael, et al.
Publicado: (2020)

Chromatin and oxygen sensing in the context of JmjC histone demethylases
por: Shmakova, Alena, et al.
Publicado: (2014)

Roles of HIF and 2-Oxoglutarate-Dependent Dioxygenases in Controlling Gene Expression in Hypoxia
por: Frost, Julianty, et al.
Publicado: (2021)

Hypoxia and Chromatin: A Focus on Transcriptional Repression Mechanisms
por: Batie, Michael, et al.
Publicado: (2018)

Cezanne (OTUD7B) regulates HIF-1α homeostasis in a proteasome-independent manner
por: Bremm, Anja, et al.
Publicado: (2014)

Evolutionary Conserved Regulation of HIF-1β by NF-κB
por: van Uden, Patrick, et al.
Publicado: (2011)

NF‐κB and HIF crosstalk in immune responses
por: D'Ignazio, Laura, et al.
Publicado: (2015)

The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH
por: Melvin, Andrew, et al.
Publicado: (2011)

TNFSF14/LIGHT, a Non-Canonical NF-κB Stimulus, Induces the HIF Pathway
por: D’Ignazio, Laura, et al.
Publicado: (2018)

HIF-1β Positively Regulates NF-κB Activity via Direct Control of TRAF6
por: D’Ignazio, Laura, et al.
Publicado: (2020)

Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
por: Mole, David R., et al.
Publicado: (2009)

Distinct roles for the hypoxia-inducible transcription factors HIF-1α and HIF-2α in human osteoclast formation and function
por: Knowles, Helen J.
Publicado: (2020)

STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia
por: Dinarello, Alberto, et al.
Publicado: (2023)

HIF-1 transcription activity: HIF1A driven response in normoxia and in hypoxia
por: Cimmino, Flora, et al.
Publicado: (2019)

HIF1α stabilization in hypoxia is not oxidant-initiated
por: Kumar, Amit, et al.
Publicado: (2021)

Functional and Transcriptional Induction of Aquaporin-1 Gene by Hypoxia; Analysis of Promoter and Role of Hif-1α
por: Abreu-Rodríguez, Irene, et al.
Publicado: (2011)

CDK-dependent phosphorylation of PHD1 on serine 130 alters its substrate preference in cells
por: Ortmann, Brian, et al.
Publicado: (2016)

Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
por: Bao, Lei, et al.
Publicado: (2018)

Transcriptional regulation of FoxM1 by HIF-1α mediates hypoxia-induced EMT in prostate cancer
por: Tang, Cong, et al.
Publicado: (2019)

Caveolin-1-Mediated Tumor Suppression Is Linked to Reduced HIF1α S-Nitrosylation and Transcriptional Activity in Hypoxia
por: Sanhueza, Carlos, et al.
Publicado: (2020)

Overexpression of bHLH domain of HIF-1 failed to inhibit the HIF-1 transcriptional activity in hypoxia
por: Sadeghi, Fatemeh, et al.
Publicado: (2020)

TfR1 interacts with the IKK complex and is involved in IKK–NF-κB signalling
por: Kenneth, Niall S., et al.
Publicado: (2012)

PHD1 Links Cell-Cycle Progression to Oxygen Sensing through Hydroxylation of the Centrosomal Protein Cep192
por: Moser, Sandra C., et al.
Publicado: (2013)

Characterization and functional analysis of hypoxia-inducible factor HIF1α and its inhibitor HIF1αn in tilapia
por: Li, Hong Lian, et al.
Publicado: (2017)

Regulation of hypoxia-inducible factor-1α by NF-κB
por: van Uden, Patrick, et al.
Publicado: (2008)

HIF1α-dependent hypoxia response in myeloid cells requires IRE1α
por: Mawambo, Gaëlle, et al.
Publicado: (2023)

Association of Age with the Expression of Hypoxia-Inducible Factors HIF-1α, HIF-2α, HIF-3α and VEGF in Lung and Heart of Tibetan Sheep
por: He, Yanyu, et al.
Publicado: (2019)

HIF-2α, but not HIF-1α, mediates hypoxia-induced up-regulation of Flt-1 gene expression in placental trophoblasts
por: Sasagawa, Tadashi, et al.
Publicado: (2018)

L3MBTL3 is induced by HIF-1α and fine tunes the HIF-1α degradation under hypoxia in vitro
por: Wang, Mengdong, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_bo8n21sp9thian0qrerem53fks