Leptin activation of mTOR pathway in intestinal epithelial cell triggers lipid droplet formation, cytokine production and increased cell proliferation

Accumulating evidence suggests that obesity and enhanced inflammatory reactions are predisposing conditions for developing colon cancer. Obesity is associated with high levels of circulating leptin. Leptin is an adipocytokine that is secreted by adipose tissue and modulates immune response and infla...

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Detalles Bibliográficos
Autores principales: Fazolini, Narayana PB, Cruz, André LS, Werneck, Miriam BF, Viola, João PB, Maya-Monteiro, Clarissa M, Bozza, Patrícia T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614828/
https://www.ncbi.nlm.nih.gov/pubmed/26017929
http://dx.doi.org/10.1080/15384101.2015.1041684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614828/
https://www.ncbi.nlm.nih.gov/pubmed/26017929
http://dx.doi.org/10.1080/15384101.2015.1041684

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