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PLGA-PEG Nanoparticles Coated with Anti-CD45RO and Loaded with HDAC Plus Protease Inhibitors Activate Latent HIV and Inhibit Viral Spread

Activating HIV-1 proviruses in latent reservoirs combined with inhibiting viral spread might be an effective anti-HIV therapeutic strategy. Active specific delivery of therapeutic drugs into cells harboring latent HIV, without the use of viral vectors, is a critical challenge to this objective. In t...

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Detalles Bibliográficos
Autores principales: Tang, Xiaolong, Liang, Yong, Liu, Xinkuang, Zhou, Shuping, Liu, Liang, Zhang, Fujina, Xie, Chunmei, Cai, Shuyu, Wei, Jia, Zhu, Yongqiang, Hou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614850/
https://www.ncbi.nlm.nih.gov/pubmed/26489856
http://dx.doi.org/10.1186/s11671-015-1112-z