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Spatio-temporal regulation of the human licensing factor Cdc6 in replication and mitosis

To maintain genome stability, the thousands of replication origins of mammalian genomes must only initiate replication once per cell cycle. This is achieved by a strict temporal separation of ongoing replication in S phase, and the formation of pre-replicative complexes in the preceding G1 phase, wh...

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Detalles Bibliográficos
Autores principales: Kalfalah, Faiza M, Berg, Elke, Christensen, Morten O, Linka, René M, Dirks, Wilhelm G, Boege, Fritz, Mielke, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614858/
https://www.ncbi.nlm.nih.gov/pubmed/25875233
http://dx.doi.org/10.1080/15384101.2014.1000182