New Insights into the RNA-Binding and E3 Ubiquitin Ligase Activities of Roquins

Roquins are a family of highly conserved RNA-binding proteins that also contain a RING-type E3 ubiquitin ligase domain. They repress constitutive decay elements containing mRNAs and play a critical role in RNA homeostasis and immunological self-tolerance. Here we present the crystal structures of th...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, Fan, Lixin, Hou, Feng, Dong, Aiping, Wang, Yun-Xing, Tong, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614863/
https://www.ncbi.nlm.nih.gov/pubmed/26489670
http://dx.doi.org/10.1038/srep15660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614863/
https://www.ncbi.nlm.nih.gov/pubmed/26489670
http://dx.doi.org/10.1038/srep15660

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