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Inhibition of peroxisome fission, but not mitochondrial fission, increases yeast chronological lifespan
Mitochondria are key players in aging and cell death. It has been suggested that mitochondrial fragmentation, mediated by the Dnm1/Fis1 organelle fission machinery, stimulates aging and cell death. This was based on the observation that Saccharomyces cerevisiae Δdnm1 and Δfis1 mutants show an enhanc...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614869/ https://www.ncbi.nlm.nih.gov/pubmed/25840089 http://dx.doi.org/10.1080/15384101.2015.1029685 |