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Role of ChIP-seq in the discovery of transcription factor binding sites, differential gene regulation mechanism, epigenetic marks and beyond

Many biologically significant processes, such as cell differentiation and cell cycle progression, gene transcription and DNA replication, chromosome stability and epigenetic silencing etc. depend on the crucial interactions between cellular proteins and DNA. Chromatin immunoprecipitation (ChIP) is a...

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Detalles Bibliográficos
Autores principales: Mundade, Rasika, Ozer, Hatice Gulcin, Wei, Han, Prabhu, Lakshmi, Lu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614920/
https://www.ncbi.nlm.nih.gov/pubmed/25486472
http://dx.doi.org/10.4161/15384101.2014.949201