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p27(Kip1) participates in the regulation of endoreplication in differentiating chick retinal ganglion cells

Nuclear DNA duplication in the absence of cell division (i.e. endoreplication) leads to somatic polyploidy in eukaryotic cells. In contrast to some invertebrate neurons, whose nuclei may contain up to 200,000-fold the normal haploid DNA amount (C), polyploid neurons in higher vertebrates show only 4...

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Detalles Bibliográficos
Autores principales: Ovejero-Benito, María C, Frade, José M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4614947/
https://www.ncbi.nlm.nih.gov/pubmed/25946375
http://dx.doi.org/10.1080/15384101.2015.1044175