Phosphorylation-dependent degradation of MEF2C contributes to regulate G2/M transition

The Myocyte Enhancer Factor 2C (MEF2C) transcription factor plays a critical role in skeletal muscle differentiation, promoting muscle-specific gene transcription. Here we report that in proliferating cells MEF2C is degraded in mitosis by the Anaphase Promoting Complex/Cyclosome (APC/C) and that thi...

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Detalles Bibliográficos
Autores principales: Badodi, Sara, Baruffaldi, Fiorenza, Ganassi, Massimo, Battini, Renata, Molinari, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615021/
https://www.ncbi.nlm.nih.gov/pubmed/25789873
http://dx.doi.org/10.1080/15384101.2015.1026519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615021/
https://www.ncbi.nlm.nih.gov/pubmed/25789873
http://dx.doi.org/10.1080/15384101.2015.1026519

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