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Nuclear translocation of Cyclin B1 marks the restriction point for terminal cell cycle exit in G2 phase
Upon DNA damage, cell cycle progression is temporally blocked to avoid propagation of mutations. While transformed cells largely maintain the competence to recover from a cell cycle arrest, untransformed cells past the G1/S transition lose mitotic inducers, and thus the ability to resume cell divisi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615111/ https://www.ncbi.nlm.nih.gov/pubmed/25486360 http://dx.doi.org/10.4161/15384101.2015.945831 |