Click chemistry armed enzyme-linked immunosorbent assay to measure palmitoylation by hedgehog acyltransferase

Hedgehog signaling is critical for correct embryogenesis and tissue development. However, on maturation, signaling is also found to be aberrantly activated in many cancers. Palmitoylation of the secreted signaling protein sonic hedgehog (Shh) by the enzyme hedgehog acyltransferase (Hhat) is required...

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Detalles Bibliográficos
Autores principales: Lanyon-Hogg, Thomas, Masumoto, Naoko, Bodakh, George, Konitsiotis, Antonio D., Thinon, Emmanuelle, Rodgers, Ursula R., Owens, Raymond J., Magee, Anthony I., Tate, Edward W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615133/
https://www.ncbi.nlm.nih.gov/pubmed/26334609
http://dx.doi.org/10.1016/j.ab.2015.08.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615133/
https://www.ncbi.nlm.nih.gov/pubmed/26334609
http://dx.doi.org/10.1016/j.ab.2015.08.025

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