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The 3'-5' exoribonuclease Dis3 regulates the expression of specific microRNAs in Drosophila wing imaginal discs

Dis3 is a highly conserved exoribonuclease which degrades RNAs in the 3'-5' direction. Mutations in Dis3 are associated with a number of human cancers including multiple myeloma and acute myeloid leukemia. In this work, we have assessed the effect of a Dis3 knockdown on Drosophila imaginal...

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Detalles Bibliográficos
Autores principales: Towler, Benjamin P, Jones, Christopher I, Viegas, Sandra C, Apura, Patricia, Waldron, Joseph A, Smalley, Sarah K, Arraiano, Cecilia M, Newbury, Sarah F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615222/
https://www.ncbi.nlm.nih.gov/pubmed/25892215
http://dx.doi.org/10.1080/15476286.2015.1040978