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Role of Merlin/NF2 Inactivation in Tumor Biology

Merlin ((Moesin-ezrin-radixin-like protein, also known as schwannomin) is a tumor suppressor protein encoded by the neurofibromatosis type 2 gene NF2. Loss of function mutations or deletions in NF2 cause Neurofibromatosis type 2 (NF2), a multiple tumor forming disease of the nervous system. NF2 is c...

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Detalles Bibliográficos
Autores principales: Petrilli, Alejandra M., Fernández-Valle, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615258/
https://www.ncbi.nlm.nih.gov/pubmed/25893302
http://dx.doi.org/10.1038/onc.2015.125