Hepatitis B virus X protein induces EpCAM expression via active DNA demethylation directed by RelA in complex with EZH2 and TET2

Chronic hepatitis B virus (HBV) infection is a major risk factor for developing hepatocellular carcinoma (HCC), and HBV X protein (HBx) acts as cofactor in hepatocarcinogenesis. In liver tumors from animals modeling HBx- and HBV-mediated hepatocarcinogenesis, downregulation of chromatin regulating p...

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Detalles Bibliográficos
Autores principales: Fan, Huitao, Zhang, Hao, Pascuzzi, Peter E., Andrisani, Ourania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615262/
https://www.ncbi.nlm.nih.gov/pubmed/25893293
http://dx.doi.org/10.1038/onc.2015.122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615262/
https://www.ncbi.nlm.nih.gov/pubmed/25893293
http://dx.doi.org/10.1038/onc.2015.122

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