Cargando…

IGFBP2 potentiates nuclear EGFR-STAT3 signaling

Insulin-like growth factor binding protein 2 (IGFBP2) is a pleiotropic oncogenic protein that has both extracellular and intracellular functions. Despite a clear causal role in cancer development, the tumor-promoting mechanisms of IGFBP2 are poorly understood. The contributions of intracellular IGFB...

Descripción completa

Detalles Bibliográficos
Autores principales: Chua, Corrine Yingxuan, Liu, Yuexin, Granberg, Kirsi J., Hu, Limei, Haapasalo, Hannu, Annala, Matti J., Cogdell, David E., Verploegen, Maartje, Moore, Lynette M., Fuller, Gregory N., Nykter, Matti, Cavenee, Webster K., Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615268/
https://www.ncbi.nlm.nih.gov/pubmed/25893308
http://dx.doi.org/10.1038/onc.2015.131