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Characterization of the UGA-recoding and SECIS-binding activities of SECIS-binding protein 2

Selenium, a micronutrient, is primarily incorporated into human physiology as selenocysteine (Sec). The 25 Sec-containing proteins in humans are known as selenoproteins. Their synthesis depends on the translational recoding of the UGA stop codon to allow Sec insertion. This requires a stem-loop stru...

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Detalles Bibliográficos
Autores principales: Bubenik, Jodi L, Miniard, Angela C, Driscoll, Donna M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615290/
https://www.ncbi.nlm.nih.gov/pubmed/25692238
http://dx.doi.org/10.1080/15476286.2014.996472