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Transmission of the PabI family of restriction DNA glycosylase genes: mobility and long-term inheritance

BACKGROUND: R.PabI is an exceptional restriction enzyme that functions as a DNA glycosylase. The enzyme excises an unmethylated base from its recognition sequence to generate apurinic/apyrimidinic (AP) sites, and also displays AP lyase activity, cleaving the DNA backbone at the AP site to generate t...

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Detalles Bibliográficos
Autores principales: Kojima, Kenji K., Kobayashi, Ichizo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615327/
https://www.ncbi.nlm.nih.gov/pubmed/26481899
http://dx.doi.org/10.1186/s12864-015-2021-3