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Silencing of Survivin Expression Leads to Reduced Proliferation and Cell Cycle Arrest in Cancer Cells
Survivin is an anti-apoptotic gene that is overexpressed in most human tumors. RNA interference using short interfering RNA (siRNA) can be used to specifically inhibit survivin expression. Tumor cells were treated with a newly designed survivin siRNA, which was modified with 2′-OMe. Cellular survivi...
Autores principales: | Li, Yuhuan, Liu, Da, Zhou, Yulin, Li, Yujing, Xie, Jing, Lee, Robert J., Cai, Yong, Teng, Lesheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615356/ https://www.ncbi.nlm.nih.gov/pubmed/26516368 http://dx.doi.org/10.7150/jca.12437 |
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