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MC1R diversity in Northern Island Melanesia has not been constrained by strong purifying selection and cannot explain pigmentation phenotype variation in the region

BACKGROUND: Variation in human skin pigmentation evolved in response to the selective pressure of ultra-violet radiation (UVR). Selection to maintain darker skin in high UVR environments is expected to constrain pigmentation phenotype and variation in pigmentation loci. Consistent with this hypothes...

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Detalles Bibliográficos
Autores principales: Norton, Heather L., Werren, Elizabeth, Friedlaender, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615358/
https://www.ncbi.nlm.nih.gov/pubmed/26482799
http://dx.doi.org/10.1186/s12863-015-0277-x