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Early origin and adaptive evolution of the GW182 protein family, the key component of RNA silencing in animals

The GW182 proteins are a key component of the miRNA-dependent post-transcriptional silencing pathway in animals. They function as scaffold proteins to mediate the interaction of Argonaute (AGO)-containing complexes with cytoplasmic poly(A)-binding proteins (PABP) and PAN2-PAN3 and CCR4-NOT deadenyla...

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Detalles Bibliográficos
Autores principales: Zielezinski, Andrzej, Karlowski, Wojciech M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615383/
https://www.ncbi.nlm.nih.gov/pubmed/26106978
http://dx.doi.org/10.1080/15476286.2015.1051302