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Interplay of Oxidative Stress and Autophagy in PAMAM Dendrimers-Induced Neuronal Cell Death

Poly-amidoamine (PAMAM) dendrimers are proposed to be one of the most promising drug-delivery nanomaterials. However, the toxicity of PAMAM dendrimers on the central nervous system seriously hinders their medical applications. The relationship between oxidative stress and autophagy induced by PAMAM...

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Detalles Bibliográficos
Autores principales: Li, Yubin, Zhu, Haiyan, Wang, Shaofei, Qian, Xiaolu, Fan, Jiajun, Wang, Ziyu, Song, Ping, Zhang, Xuesai, Lu, Weiyue, Ju, Dianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615738/
https://www.ncbi.nlm.nih.gov/pubmed/26516373
http://dx.doi.org/10.7150/thno.13181