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Conserved linker regions and their regulation determine multiple chromatin-binding modes of UHRF1

Ubiquitin-like with PHD and RING Finger domains 1 (UHRF1) is an important nuclear protein that is mutated and aberrantly expressed in many tumors. The protein integrates different chromatin modifications and is essential for their maintenance throughout the cell cycle. Separate chromatin-binding mod...

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Detalles Bibliográficos
Autores principales: Tauber, Maria, Fischle, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615792/
https://www.ncbi.nlm.nih.gov/pubmed/25891992
http://dx.doi.org/10.1080/19491034.2015.1026022