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Oestrogen receptor alpha in pulmonary hypertension

AIMS: Pulmonary arterial hypertension (PAH) occurs more frequently in women with mutations in bone morphogenetic protein receptor type 2 (BMPR2) and dysfunctional BMPR2 signalling underpinning heritable PAH. We have previously shown that serotonin can uncover a pulmonary hypertensive phenotype in BM...

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Detalles Bibliográficos
Autores principales: Wright, Audrey F., Ewart, Marie-Ann, Mair, Kirsty, Nilsen, Margaret, Dempsie, Yvonne, Loughlin, Lynn, Maclean, Margaret R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615797/
https://www.ncbi.nlm.nih.gov/pubmed/25765937
http://dx.doi.org/10.1093/cvr/cvv106