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Positional changes of a pluripotency marker gene during structural reorganization of fibroblast nuclei in cloned early bovine embryos

Cloned bovine preimplantation embryos were generated by somatic cell nuclear transfer (SCNT) of bovine fetal fibroblasts with a silent copy of the pluripotency reporter gene GOF, integrated at a single site of a chromosome 13. GOF combines the regulatory Oct4/Pou5f1 sequence with the coding sequence...

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Detalles Bibliográficos
Autores principales: Popken, Jens, Koehler, Daniela, Brero, Alessandro, Wuensch, Annegret, Guengoer, Tuna, Thormeyer, Tobias, Wolf, Eckhard, Cremer, Thomas, Zakhartchenko, Valeri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4615807/
https://www.ncbi.nlm.nih.gov/pubmed/25495180
http://dx.doi.org/10.4161/19491034.2014.970107